Thymine DNA glycosylase (TDG) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3A12]

CAT#: TA808511AM

TDG mouse monoclonal antibody, clone OTI3A12 (formerly 3A12), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI3A12" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of thymine-DNA glycosylase (TDG)
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI3A12
Applications IHC, WB
Recommend Dilution IHC 1:150
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 160-253 of human TDG(NP_003202) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 45.9 kDa
Gene Name thymine DNA glycosylase
Background The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Synonyms hTDG
Reference Data
Protein Families Druggable Genome
Protein Pathways Base excision repair
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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