MAP3K8 Mouse Monoclonal Antibody [Clone ID: OTI2E10]
CAT#: TA808427
MAP3K8 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI2E10" antibodies (4)
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 2,700.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI2E10 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 277-461 of human MAP3K8(NP_005195) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 52.7 kDa |
Gene Name | mitogen-activated protein kinase kinase kinase 8 |
Database Link | |
Background | This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011] |
Synonyms | AURA2; c-COT; COT; EST; ESTF; MEKK8; Tpl-2; TPL2 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF808427 | Carrier-free (BSA/glycerol-free) MAP3K8 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10) |
CNY 3,999.00 |
|
TA808427AM | MAP3K8 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10), Biotinylated |
CNY 3,990.00 |
|
TA808427BM | MAP3K8 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10), HRP conjugated |
CNY 3,990.00 |
|
TA808427S | MAP3K8 mouse monoclonal antibody, clone OTI2E10 (formerly 2E10) |
CNY 800.00 |