CDC42 binding protein kinase alpha (CDC42BPA) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI12C12]

Specifications

Product Data
Clone Name	OTI12C12
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1419-1638 of human CDC42BPA(NP_055641) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	185.9 kDa
Gene Name	CDC42 binding protein kinase alpha
Database Link	NP_055641 Entrez Gene 114116 RatEntrez Gene 226751 MouseEntrez Gene 8476 Human UniProt ID Q5VT25
Background	The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]
Synonyms	MRCK; MRCKA; PK428
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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