DR5 (TNFRSF10B) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1B9]

CAT#: TA807279BM

TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9), HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI1B9" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Recombinant protein of human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, 20 µg
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Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1
    • 100 ug

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Specifications

Product Data
Clone Name OTI1B9
Applications IHC, WB
Recommend Dilution IHC 1:150
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 203-411 of human TNFRSF10B(NP_671716) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 39.4 kDa
Gene Name tumor necrosis factor receptor superfamily member 10b
Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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