ROR beta (RORB) Mouse Monoclonal Antibody [Clone ID: OTI4B7]

Specifications

Product Data
Clone Name	OTI4B7
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-260 of human RORB(NP_008845) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.9 kDa
Gene Name	RAR related orphan receptor B
Database Link	NP_008845 Entrez Gene 225998 MouseEntrez Gene 309288 RatEntrez Gene 6096 Human UniProt ID Q92753
Background	The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Synonyms	bA133M9.1; NR1F2; ROR-BETA; RZR-BETA; RZRB
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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