SHARP1 (BHLHE41) Mouse Monoclonal Antibody [Clone ID: OTI7E8]

Specifications

Product Data
Clone Name	OTI7E8
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-297 of human BHLHE41(NP_110389) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.3 kDa
Gene Name	basic helix-loop-helix family member e41
Database Link	NP_110389 Entrez Gene 79365 Human UniProt ID Q9C0J9
Background	This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014]
Synonyms	BHLHB3; DEC2; hDEC2; SHARP1
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Circadian rhythm - mammal

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