Calpain 5 (CAPN5) Mouse Monoclonal Antibody [Clone ID: OTI4E11]

Specifications

Product Data
Clone Name	OTI4E11
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 274-578 of human CAPN5 (NP_004046) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	73 kDa
Gene Name	calpain 5
Database Link	NP_004046 Entrez Gene 12337 MouseEntrez Gene 171495 RatEntrez Gene 726 Human UniProt ID O15484
Background	Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]
Synonyms	ADNIV; HTRA3; nCL-3; VRNI
Reference Data
Protein Families	Druggable Genome, Protease

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