CSEN (KCNIP3) Mouse Monoclonal Antibody [Clone ID: OTI3A12]

Specifications

Product Data
Clone Name	OTI3A12
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human KCNIP3 (NP_038462) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.1 kDa
Gene Name	potassium voltage-gated channel interacting protein 3
Database Link	NP_038462 Entrez Gene 56461 MouseEntrez Gene 65199 RatEntrez Gene 30818 Human UniProt ID Q9Y2W7
Background	This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms	CSEN; DREAM; KCHIP3
Reference Data
Protein Families	Druggable Genome, Transcription Factors, Transmembrane

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