DDOST Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2B4]

Specifications

Product Data
Clone Name	OTI2B4
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 131-378 of human DDOST (NP_005207) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46.1 kDa
Gene Name	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Database Link	NP_005207 Entrez Gene 13200 MouseEntrez Gene 313648 RatEntrez Gene 1650 Human UniProt ID P39656
Background	This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
Synonyms	AGER1; CDG1R; OKSWcl45; OST; OST48; WBP1
Reference Data
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, N-Glycan biosynthesis

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