ITGB3BP Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4H1]

Specifications

Product Data
Clone Name	OTI4H1
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ITGB3BP (NP_055103) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20 kDa
Gene Name	integrin subunit beta 3 binding protein
Database Link	NP_055103 Entrez Gene 23421 Human UniProt ID Q13352
Background	This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Synonyms	CENP-R; CENPR; HSU37139; NRIF3; TAP20
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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