NR2C1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4C7]

Specifications

Product Data
Clone Name	OTI4C7
Applications	IHC, WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-237 of human NR2C1 (NP_001027458) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51 kDa
Gene Name	nuclear receptor subfamily 2 group C member 1
Database Link	NP_001027458 Entrez Gene 22025 MouseEntrez Gene 252924 RatEntrez Gene 7181 Human UniProt ID P13056
Background	This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Synonyms	TR2
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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