P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: OTI6H2]
CAT#: TA801007S
ABCB1 mouse monoclonal antibody, clone OTI6H2 (formerly 6H2)
Size: 100 ul
View other "OTI6H2" antibodies (4)
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CNY 800.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | OTI6H2 |
Applications | IHC, WB |
Recommend Dilution | WB 1:1000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | ATP binding cassette subfamily B member 1 |
Database Link | |
Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008] |
Synonyms | ABC20; CD243; CLCS; GP170; MDR1; p-170; P-GP; PGY1 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | ABC transporters |
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抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801007 | Carrier-free (BSA/glycerol-free) ABCB1 mouse monoclonal antibody, clone OTI6H2 (formerly 6H2) |
CNY 3,999.00 |
|
TA801007 | ABCB1 mouse monoclonal antibody, clone OTI6H2 (formerly 6H2) |
CNY 1,999.00 |
|
TA801007AM | ABCB1 mouse monoclonal antibody,clone 6H2, Biotinylated |
CNY 3,990.00 |
|
TA801007BM | ABCB1 mouse monoclonal antibody,clone 6H2, HRP conjugated |
CNY 3,990.00 |
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