Thymidine Phosphorylase (TYMP) Mouse Monoclonal Antibody [Clone ID: OTI1E7]

Specifications

Product Data
Clone Name	OTI1E7
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 311-482 of human TYMP (NP_001944) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49.8 kDa
Gene Name	thymidine phosphorylase
Database Link	NP_001944 Entrez Gene 1890 Human UniProt ID P19971
Background	This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
Synonyms	ECGF; ECGF1; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; TP
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Bladder cancer, Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

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