OSBPL2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E6]

Specifications

Product Data
Clone Name	OTI2E6
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 258-480 of human OSBPL2 (NP_653081) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	55 kDa
Gene Name	oxysterol binding protein like 2
Database Link	NP_653081 Entrez Gene 228983 MouseEntrez Gene 296461 RatEntrez Gene 9885 Human UniProt ID Q9H1P3
Background	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms	DFNA67; DNFA67; ORP-2; ORP2
Reference Data

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