MAGEB1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B12]

Specifications

Product Data
Clone Name	OTI2B12
Applications	IHC, WB
Recommend Dilution	IHC 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MAGEB1 (NP_796379) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38.9 kDa
Gene Name	MAGE family member B1
Database Link	NP_796379 Entrez Gene 4112 Human UniProt ID P43366
Background	This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq]
Synonyms	CT3.1; DAM10; MAGE-Xp; MAGEL1
Reference Data

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