S Protein Rabbit Monoclonal Antibody [Clone ID: OTIR4A8]

Specifications

Product Data
Clone Name	OTIR4A8
Applications	ELISA
Recommend Dilution	ELISA 1:5000-10000
Reactivity	SARS-CoV-2
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant fusion protein of SARS-CoV-2 Spike RBD Protein and Virion Surface Domain of Membrane Protein (M-protein) produced in HEK293
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Predicted Protein Size	34kDa
Gene Name	S Protein
Database Link	Entrez Gene 43740568 SARS-CoV-2
Background	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Reference Data

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