Cathepsin B (CTSB) Rabbit Monoclonal Antibody [Clone ID: OTIR1C4]

CAT#: TA591040

Rabbit monoclonal anti-CATB antibody for SISCAPA, clone OTIR1C4



Need it in bulk or conjugated?
Get a free quote

CNY 4,390.00


货期*
4周

规格
    • 100 ul

Product images

经常一起买 (5)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human cathepsin B (CTSB), transcript variant 5, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of cathepsin B (CTSB), transcript variant 4
    • 100 ug

CNY 3,080.00


Recombinant protein of human cathepsin B (CTSB), transcript variant 5, 100 µg
    • 100 ug

CNY 9,998.00


Transient overexpression lysate of cathepsin B (CTSB), transcript variant 5
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTIR1C4
Applications SISCAPA
Reactivity Human
Host Rabbit
Clonality Monoclonal
Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CTSB (NP_680093). The exact sequence is proprietary.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration Lot dependent; please refer to CoA along with shipment
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 37.82 kDa
Gene Name cathepsin B
Background This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015]
Synonyms APPS; CPSB; RECEUP
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Antigen processing and presentation, Lysosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...