Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

CAT#: TA590345

Rabbit Polyclonal Nucleophosmin Antibody



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CNY 5,302.00


货期*
4周

规格
    • 100 ug

Product images

经常一起买 (4)
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Recombinant protein of human nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 2, 100 µg
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Specifications

Product Data
Applications ELISA
Recommend Dilution WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 0.96mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name nucleophosmin 1
Background The CD246 antigen, or ALK (Anaplastic Lymphoma Kinase; neural tyrosine kinase) is a 200 kDa transmembrane molecule expressed only in neural tissues (weakly) and by the rhabdomyosarcoma Rh30 cell line. The alk gene is on chromosome 2. Upon translocation between chromosome 2 and chromosome 5 [t(2;5)], the alk gene fuses with the npm gene. NPM, also known as nucleophosmin or B23, is an ubiquitous nucleolar phosphoprotein involved in the transport of pre-ribosomal components between the nucleolus and the cytoplasm. The chimeric product resulting from t(2;5) translocation is a protein of 80 kDa with the N-terminal portion of NPM linked to the complete intracellular portion of ALK. Karpas 299 and SU-DHL-1 lymphoid cell lines strongly express NPM-ALK.
Synonyms B23; NPM
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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