SOCS2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: 1:100-1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	DNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Formulation	20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration	1.00547 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	suppressor of cytokine signaling 2
Database Link	NP_003868 Entrez Gene 8835 Human UniProt ID O14508
Background	The SOCS2 (suppressor of cytokine signaling-2) protein is a 23 kD cytoplasmic protein that contains a SOCS box and an SH2 domain. SOCS2 has been shown to be involved in postnatal growth hormone signaling, IGF-1 signaling via the JAK/STAT pathway, and neuronal differentiation. SOCS2 is induced by erythropoietin, GM-CSF, IL-10, and IFN- gamma. SOCS2 has been shown to interact with the IGF-1 and growth hormone receptors. The Poly6153 antibody recognizes the N-terminal region of human SOCS2 and has been shown to be useful for Western blotting.
Synonyms	CIS2; Cish2; SOCS-2; SSI-2; SSI2; STATI2
Note	This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus

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