Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Mouse Monoclonal Antibody [Clone ID: OTI1F3]

Specifications

Product Data
Clone Name	OTI1F3
Applications	IF, IHC, WB
Recommend Dilution	WB 1:4000, IHC 1:150, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HSD17B4(NP_000405) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	79.5 kDa
Gene Name	hydroxysteroid 17-beta dehydrogenase 4
Database Link	NP_000405 Entrez Gene 15488 MouseEntrez Gene 3295 Human UniProt ID P51659
Background	The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008]
Synonyms	DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Primary bile acid biosynthesis

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