EPCAM Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B8]

Specifications

Product Data
Clone Name	OTI2B8
Applications	IF, IHC, WB
Recommend Dilution	WB 1:2000, IF 1:100, IHC: 1:150-1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human EPCAM(NP_002345) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32.7 kDa
Gene Name	epithelial cell adhesion molecule
Database Link	NP_002345 Entrez Gene 4072 Human UniProt ID P16422
Background	This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Synonyms	DIAR5; EGP-2; EGP40; EGP314; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transmembrane

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