HGS Mouse Monoclonal Antibody [Clone ID: OTI3H7]

Specifications

Product Data
Clone Name	OTI3H7
Applications	IF, WB
Recommend Dilution	WB 1:4000, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HGS(NP_004703) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	hepatocyte growth factor-regulated tyrosine kinase substrate
Database Link	NP_004703 Entrez Gene 15239 MouseEntrez Gene 56084 RatEntrez Gene 9146 Human UniProt ID O14964
Background	The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
Synonyms	HRS
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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