Phosphoribosyl pyrophosphate amidotransferase (PPAT) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1B8]

Specifications

Product Data
Clone Name	OTI1B8
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 42-278 of human PPAT(NP_002694) produced in E.coli.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	57.2 kDa
Gene Name	phosphoribosyl pyrophosphate amidotransferase
Database Link	NP_002694 Entrez Gene 117544 RatEntrez Gene 231327 MouseEntrez Gene 611407 DogEntrez Gene 694868 MonkeyEntrez Gene 5471 Human UniProt ID Q06203
Background	The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	ATASE; GPAT; PRAT
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism

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