FDFT1 Mouse Monoclonal Antibody [Clone ID: OTI2F10]

Specifications

Product Data
Clone Name	OTI2F10
Applications	IF, IHC, WB
Recommend Dilution	WB 1:200~500, IHC 1:150, IF 1:100
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FDFT1(NP_004453) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.93 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	47.9 kDa
Gene Name	farnesyl-diphosphate farnesyltransferase 1
Database Link	NP_004453 Entrez Gene 14137 MouseEntrez Gene 29580 RatEntrez Gene 696396 MonkeyEntrez Gene 2222 Human UniProt ID P37268
Background	This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
Synonyms	DGPT; ERG9; SQS; SS
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Steroid biosynthesis

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