COASY Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3B3]

Specifications

Product Data
Clone Name	OTI3B3
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human COASY(NP_079509) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62.1 kDa
Gene Name	Coenzyme A synthase
Database Link	NP_079509 Entrez Gene 71743 MouseEntrez Gene 287711 RatEntrez Gene 80347 Human UniProt ID Q13057
Background	Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]). [supplied by OMIM]
Synonyms	DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1
Reference Data
Protein Pathways	Metabolic pathways, Pantothenate and CoA biosynthesis

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