CARKL (SHPK) Mouse Monoclonal Antibody [Clone ID: OTI2A12]

Specifications

Product Data
Clone Name	OTI2A12
Applications	FC, WB
Recommend Dilution	WB 1:2000, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SHPK(NP_037408) produced in HEK293 cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.25 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.3 kDa
Gene Name	sedoheptulokinase
Database Link	NP_037408 Entrez Gene 74637 MouseEntrez Gene 287479 RatEntrez Gene 23729 Human UniProt ID Q9UHJ6
Background	The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	CARKL; SHK
Reference Data
Protein Families	Druggable Genome

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