PNPO Mouse Monoclonal Antibody [Clone ID: OTI2F8]

Specifications

Product Data
Clone Name	OTI2F8
Applications	FC, IF, WB
Recommend Dilution	WB 1:500, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PNPO(NP_060599) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.8 kDa
Gene Name	pyridoxamine 5'-phosphate oxidase
Database Link	NP_060599 Entrez Gene 64533 RatEntrez Gene 103711 MouseEntrez Gene 55163 Human UniProt ID Q9NVS9
Background	The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	HEL-S-302; PDXPO
Reference Data
Protein Pathways	Metabolic pathways, Vitamin B6 metabolism

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