Monoacylglycerol Lipase (MGLL) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B6]

Specifications

Product Data
Clone Name	OTI2B6
Applications	FC, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MGLL (NP_009214) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.1 kDa
Gene Name	monoglyceride lipase
Database Link	NP_009214 Entrez Gene 11343 Human UniProt ID Q99685
Background	This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Synonyms	HU-K5; HUK5; MAGL; MGL
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Glycerolipid metabolism, Metabolic pathways

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