IKB zeta (NFKBIZ) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E8]

Specifications

Product Data
Clone Name	OTI1E8
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	77.9 kDa
Gene Name	NFKB inhibitor zeta
Database Link	NP_113607 Entrez Gene 304005 RatEntrez Gene 64332 Human UniProt ID Q9BYH8
Background	This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms	IKBZ; INAP; MAIL
Reference Data
Protein Families	Druggable Genome

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