PDHA1 Mouse Monoclonal Antibody [Clone ID: OTI2C10]
CAT#: TA502696
PDHA1 mouse monoclonal antibody, clone OTI2C10 (formerly 2C10)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI2C10" antibodies (4)
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 2,700.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI2C10 |
Applications | FC, IF, WB |
Recommend Dilution | WB 1:2000, IF 1:100, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PDHA1 (NP_000275) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.75 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 40.2 kDa |
Gene Name | pyruvate dehydrogenase E1 subunit alpha 1 |
Database Link | |
Background | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Synonyms | PDHA; PDHAD; PDHCE1A; PHE1A |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Butanoate metabolism, Citrate cycle (TCA cycle), Glycolysis / Gluconeogenesis, Metabolic pathways, Pyruvate metabolism, Valine, leucine and isoleucine biosynthesis |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF502696 | Carrier-free (BSA/glycerol-free) PDHA1 mouse monoclonal antibody, clone OTI2C10 (formerly 2C10) |
CNY 3,999.00 |
|
TA502696AM | PDHA1 mouse monoclonal antibody, clone OTI2C10 (formerly 2C10), Biotinylated |
CNY 3,990.00 |
|
TA502696BM | PDHA1 mouse monoclonal antibody, clone OTI2C10 (formerly 2C10), HRP conjugated |
CNY 3,990.00 |
|
TA502696S | PDHA1 mouse monoclonal antibody, clone OTI2C10 (formerly 2C10) |
CNY 800.00 |