PIK3AP1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7B12]

Specifications

Product Data
Clone Name	OTI7B12
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PIK3AP1 (NP_689552) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	90.2 kDa
Gene Name	phosphoinositide-3-kinase adaptor protein 1
Database Link	NP_689522 Entrez Gene 294048 RatEntrez Gene 118788 Human UniProt ID Q6ZUJ8
Background	Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).
Synonyms	BCAP
Reference Data
Protein Families	Druggable Genome
Protein Pathways	B cell receptor signaling pathway

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