MTMR14 Mouse Monoclonal Antibody [Clone ID: OTI7F2]

Specifications

Product Data
Clone Name	OTI7F2
Applications	FC, IF, WB
Recommend Dilution	WB 1:2000, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MTMR14 (NP_001070993) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72.0 kDa
Gene Name	myotubularin related protein 14
Database Link	NP_001070993 Entrez Gene 97287 MouseEntrez Gene 312634 RatEntrez Gene 64419 Human UniProt ID Q8NCE2
Background	This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
Synonyms	C3orf29
Reference Data
Protein Families	Druggable Genome, Phosphatase, Secreted Protein

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