HIF1 beta (ARNT) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1D10]
CAT#: TA501148BM
Anti-ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1D10 (formerly 1D10), HRP conjugated
Conjugation: Unconjugated Biotin
View other "OTI1D10" antibodies (5)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI1D10 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:50, IF 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ARNT (NP_001659) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 86.5 kDa |
Gene Name | aryl hydrocarbon receptor nuclear translocator |
Database Link | |
Background | The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1). A t(1;12)(q21;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Three alternatively spliced variants encoding different isoforms have been described for this gene. |
Synonyms | bHLHe2; HIF-1-beta; HIF-1beta; HIF1-beta; HIF1B; HIF1BETA; TANGO |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Pathways in cancer, Renal cell carcinoma |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF501148 | Carrier-free (BSA/glycerol-free) ARNT mouse monoclonal antibody, clone OTI1D10 (formerly 1D10) |
CNY 3,999.00 |
|
TA501148 | Anti-ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1D10 (formerly 1D10) |
CNY 1,999.00 |
|
TA501148AM | Anti-ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1D10 (formerly 1D10), Biotinylated |
CNY 3,990.00 |
|
TA501148S | Anti-ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1D10 (formerly 1D10) |
CNY 800.00 |
|
TA600042 | ARNT mouse monoclonal capture antibody, validated for Luminex assays |
CNY 2,600.00 |
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