NIT1 Mouse Monoclonal Antibody [Clone ID: OTI4D12]

Specifications

Product Data
Clone Name	OTI4D12
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NIT1 (NP_005591) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.66 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35.7 kDa
Gene Name	nitrilase 1
Database Link	NP_005591 Entrez Gene 27045 MouseEntrez Gene 289222 RatEntrez Gene 4817 Human UniProt ID Q86X76
Background	Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
Synonyms	MGC57670
Reference Data

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