XRCC1 Mouse Monoclonal Antibody [Clone ID: OTI2F8]
CAT#: TA500880S
Anti-XRCC1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
Size: 100 ul
View other "OTI2F8" antibodies (4)
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CNY 800.00
Cited in 1 publication. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI2F8 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:2000, IHC 1:50, IF 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.64 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 69.5 kDa |
Gene Name | X-ray repair cross complementing 1 |
Database Link | |
Background | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
Synonyms | RCC |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
---|
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
,Wang, H;Guo, W;Mitra, J;Hegde, PM;Vandoorne, T;Eckelmann, BJ;Mitra, S;Tomkinson, AE;Van Den Bosch, L;Hegde, ML;,
Nat Commun
,PubMed ID 30206235
[XRCC1]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500880 | Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8) |
CNY 3,999.00 |
|
TA500880 | Anti-XRCC1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8) |
CNY 1,999.00 |
|
TA500880AM | Anti-XRCC1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8), Biotinylated |
CNY 3,990.00 |
|
TA500880BM | Anti-XRCC1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8), HRP conjugated |
CNY 3,990.00 |