ERK2 (MAPK1) Mouse Monoclonal Antibody [Clone ID: OTI6F8]
CAT#: TA500468
Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI6F8" antibodies (6)
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Specifications
Product Data | |
Clone Name | OTI6F8 |
Applications | FC, IHC, IP, WB |
Recommend Dilution | WB 1:1000~2000, IHC 1:50, FLOW 1:100, IP 2ug/500ul |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human MAPK1(NP_620407) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 41.4 kDa |
Gene Name | mitogen-activated protein kinase 1 |
Database Link | |
Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Synonyms | ERK; ERK-2; ERK2; ERT1; MAPK2; NS13; p38; p40; p41; p41mapk; p42-MAPK; P42MAPK; PRKM1; PRKM2 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Acute myeloid leukemia, Adherens junction, Alzheimer's disease, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Non-small cell lung cancer, Oocyte meiosis, Pancreatic cancer, Pathways in cancer, Prion diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, TGF-beta signaling pathway, Thyroid cancer, Toll-like receptor signaling pathway, Type II diabetes mellitus, Vascular smooth muscle contraction, VEGF signaling pathway |
Citations (5)
The use of this Antibodies has been cited in the following citations: |
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Microcurrent Stimulation Triggers MAPK Signaling and TGF-β1 Release in Fibroblast and Osteoblast-Like Cell Lines
,Konstantinou, E;Zagoriti, Z;Pyriochou, A;Poulas, K;,
Cells
,PubMed ID 32825091
[MAPK1]
|
Alteration of Cytoskeleton Morphology and Gene Expression in Human Breast Cancer Cells under Simulated Microgravity
,Strube, F;Infanger, M;Wehland, M;Delvinioti, X;Romswinkel, A;Dietz, C;Kraus, A;,
Cell J
,PubMed ID 31606974
[MAPK1]
|
Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression
,Li, Y;Ma, G;Lv, Y;Su, J;Li, G;Chen, X;,
Molecules
,PubMed ID 31117291
[MAPK1]
|
The Elevated ASK1 Expression Inhibits Proliferation and Invasion in Gastric Cancer HGC-27 Cells
,Wan, X;Shi, L;Ma, X;Tang, H;Wu, G;,
Anat Rec (Hoboken) 2018
,PubMed ID 30324658
[MAPK1]
|
A natural antioxidant, tannic acid mitigates iron-overload induced hepatotoxicity in Swiss albino mice through ROS regulation
,Basu, T;Panja, S;Shendge, AK;Das, A;Mandal, N;,
Environ. Toxicol.
,PubMed ID 29446234
[MAPK1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500468 | Carrier-free (BSA/glycerol-free) MAPK1 mouse monoclonal antibody, clone OTI6F8 (formerly 6F8) |
CNY 3,999.00 |
|
TA500468AM | Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8), Biotinylated |
CNY 3,990.00 |
|
TA500468BM | Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8), HRP conjugated |
CNY 3,990.00 |
|
TA500468S | Anti-MAPK1 (ERK2) mouse monoclonal antibody, clone OTI6F8 (formerly 6F8) |
CNY 800.00 |
|
TA600063 | MAPK1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays |
CNY 2,600.00 |
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TA700063 | MAPK1 biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
CNY 2,700.00 |