GFAP Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D11]

Specifications

Product Data
Clone Name	OTI4D11
Applications	IF, WB
Recommend Dilution	WB 1:2000, IHC: 1:50-1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human GFAP expression vector
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49.9 kDa
Gene Name	glial fibrillary acidic protein
Database Link	NP_002046 Entrez Gene 14580 MouseEntrez Gene 24387 RatEntrez Gene 2670 Human UniProt ID P14136
Background	This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Synonyms	ALXDRD
Reference Data
Protein Families	ES Cell Differentiation/IPS

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