STAT5A Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4H1]
CAT#: TA500006AM
Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1), Biotinylated
Conjugation: Unconjugated HRP
View other "OTI4H1" antibodies (6)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI4H1 |
Applications | IHC, WB |
Recommend Dilution | WB 1:200~500, IHC 1:50 |
Reactivity | Human, Rat, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 2-104 of human Stat5a (NP_003143) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 90.5 kDa |
Gene Name | signal transducer and activator of transcription 5A |
Database Link | |
Background | Stat5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. |
Synonyms | MGF; STAT5 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
Protein Pathways | Acute myeloid leukemia, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500006 | Carrier-free (BSA/glycerol-free) Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) |
CNY 3,999.00 |
|
TA500006 | Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) |
CNY 1,999.00 |
|
TA500006BM | Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1), HRP conjugated |
CNY 3,990.00 |
|
TA500006S | Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) |
CNY 800.00 |
|
TA600173 | STAT5A mouse monoclonal capture antibody, validated for ELISA and Luminex assays |
CNY 3,600.00 |
|
TA700170 | STAT5A biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays |
CNY 2,700.00 |