Phospho-GCN2 (EIF2AK4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:1000 - 1:5000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic phosphorylated peptide around T899 of human Phospho-GCN2-T899 (NP_001013725.2).
Formulation	Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	187kDa - Observed MW: 220kDa
Gene Name	eukaryotic translation initiation factor 2 alpha kinase 4
Database Link	Entrez Gene 440275 Human UniProt ID Q9P2K8
Background	This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Synonyms	GCN2; PVOD2
Reference Data

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