Phospho-GCN2 (EIF2AK4) Rabbit Polyclonal Antibody
CNY 7,740.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:1000 - 1:5000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic phosphorylated peptide around T899 of human Phospho-GCN2-T899 (NP_001013725.2). |
Formulation | Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 187kDa - Observed MW: 220kDa |
Gene Name | eukaryotic translation initiation factor 2 alpha kinase 4 |
Database Link | |
Background | This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. |
Synonyms | GCN2; PVOD2 |
Reference Data |
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