LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]

CAT＃: TA400001

Anti-LGR5 mouse mAb, clone OTI2A2, PE conjugated

Conjugation: DyLight488 DyLight550 DyLight633 PE

Datasheet
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CNY 3,790.00

货期*
4周
规格
    • 100 ul
Cited in 24 publications.

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Specifications

Product Data
Clone Name OTI2A2
Applications FC, IHC
Recommend Dilution FC 1:50
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T Cell.
Formulation PBS (pH7.4) containing 0.02% NaN3; store at 4C, do not freeze
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Conjugation PE
Storage Condition Store at 4°C.
Predicted Protein Size 99.8 kDa
Gene Name leucine rich repeat containing G protein-coupled receptor 5
Database Link
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (24)

The use of this Antibodies has been cited in the following citations:
Lactobacillus rhamnosus GG Promotes Recovery of the Colon Barrier in Septic Mice through Accelerating ISCs Regeneration. ,null, Nutrients ,PubMed ID 36771378 [LGR5]
Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity ,null, Journal of Medicinal Chemistry ,PubMed ID 36634271 [LGR5]
Mouse organoid culture is a suitable model to study esophageal ion transport mechanisms. ,null, American journal of physiology. Cell physiology ,PubMed ID 34524930 [LGR5]
Colon Crypts of Subjects With Familial Adenomatous Polyposis Show an Increased Number of LGR5+ Ectopic Stem Cells ,null, Clinical and Translational Gastroenterology ,PubMed ID 33999013 [LGR5]
The Hippo Pathway Effector YAP1 Regulates Intestinal Epithelial Cell Differentiation ,null, Cells ,PubMed ID 32823612 [LGR5]
FoxA2 inhibits the proliferation of hepatic progenitor cells by reducing PI3K/Akt/HK2-mediated glycolysis. ,null, Journal of cellular physiology ,PubMed ID 32495363 [LGR5]
Evaluation of Intestinal Epithelial Barrier Function in Inflammatory Bowel Diseases Using Murine Intestinal Organoids ,null, Tissue Engineering and Regenerative Medicine ,PubMed ID 32594459 [LGR5]
Clinicopathologic and prognostic significance of LGR5, a cancer stem cell marker in patients with colorectal cancer ,null, Colorectal Cancer ,PubMed ID 32038737 [LGR5]
Surface expression marker profile in colon cancer cell lines and sphere-derived cells suggests complexity in CD26+ cancer stem cells subsets ,null, Biology Open ,PubMed ID 31285270 [LGR5]
Acute exposure to deoxynivalenol inhibits porcine enteroid activity via suppression of the Wnt/β-catenin pathway. ,null, Toxicology letters ,PubMed ID 30690062 [LGR5]
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers ,null, Oncogene ,PubMed ID 29343849 [LGR5]
LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway ,null, Oncogenesis ,PubMed ID 30089773 [LGR5]
The Stem Cell Marker Lgr5 Defines a Subset of Postmitotic Neurons in the Olfactory Bulb ,null, The Journal of Neuroscience ,PubMed ID 28847812 [LGR5]
Cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids ,Nakaoka, T;Saito, Y;Shimamoto, Y;Muramatsu, T;Kimura, M;Kanai, Y;Saito, H;, Cancer Sci. ,PubMed ID 28092415 [LGR5]
Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase ,null, Oncotarget ,PubMed ID 27705927 [LGR5]
LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1 ,null, PLoS ONE ,PubMed ID 28033430 [LGR5]
RSPO2 enriches LGR5(+) spheroid colon cancer stem cells and promotes its metastasis by epithelial-mesenchymal transition ,Zhang, S;Han, X;Wei, B;Fang, J;Wei, H;, Am J Transl Res ,PubMed ID 27158331 [LGR5]
Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures ,Fraveto, A;Cardinale, V;Bragazzi, MC;Giuliante, F;De Rose, AM;Grazi, GL;Napoletano, C;Semeraro, R;Lustri, AM;Costantini, D;Nevi, L;Di Matteo, S;Renzi, A;Carpino, G;Gaudio, E;Alvaro, D;, PLoS ONE ,PubMed ID 26571380 [LGR5]
Synthetic, Non-saccharide, Glycosaminoglycan Mimetics Selectively Target Colon Cancer Stem Cells ,null, ACS Chemical Biology ,PubMed ID 24968014 [LGR5]
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo ,null, Oncotarget ,PubMed ID 25895029 [LGR5]
A Human Colonic Crypt Culture System to Study Regulation of Stem Cell-Driven Tissue Renewal and Physiological Function ,Parris, A;Williams, MR;, Methods Mol. Biol. ,PubMed ID 25762290 [LGR5]
[Human; IHC]
B7-H1 enhances proliferation ability of gastric cancer stem-like cells as a receptor ,Yang, Y;Wu, K;Zhao, E;Li, W;Shi, L;, ONCOLOGY LETTERS ,PubMed ID 25789052 [LGR5]
The use of murine-derived fundic organoids in studies of gastric physiology ,Schumacher, MA;Aihara, E;Feng, R;Engevik, A;Shroyer, NF;Ottemann, KM;Worrell, RT;Montrose, MH;Shivdasani, RA;Zavros, Y;, J. Physiol. (Lond.) ,PubMed ID 25605613 [LGR5]
[Mouse; FC]
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis ,null, Biomaterials ,PubMed ID 24345734 [LGR5]

Other Versions

SKU Description Size Price
TA400002 Anti-LGR5 mouse mAb, clone OTI2A2, DyLight 488 conjugated
    • 100 ul

CNY 3,790.00

TA400003 Anti-LGR5 mouse mAb, clone OTI2A2, DyLight 550 conjugated
    • 100 ul

CNY 3,790.00

TA400006 Anti-LGR5 mouse mAb, clone OTI2A2, HRP conjugated
    • 50 ug

CNY 3,790.00

TA400007 Anti-LGR5 mouse mAb, clone OTI2A2, bionylated
    • 50 ug

CNY 3,790.00

TA400031 Anti-LGR5 mouse mAb, clone OTI2A2, DyLight633 conjugated
    • 100 ul

CNY 3,790.00

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