p38 (CRK) Rabbit Polyclonal Antibody

CAT#: TA392884

Crk2 (phospho-Y221) polyclonal antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,350.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic phosphopeptide derived from human Crk2 around the phosphorylation site of Tyrosine 221.
Specificity Crk2 (phospho-Y221) polyclonal antibody detects endogenous levels of Crk2 protein only when phosphorylated at Tyr221.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 34 kDa
Gene Name v-crk avian sarcoma virus CT10 oncogene homolog
Background Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor I (IGF-I) and might be involved in the IGF-I receptor signalling pathway.
Synonyms Adapter molecule crk; CRK; CRKII; p38 CRK; Proto-oncogene c-Crk
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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