CDC40 Rabbit Polyclonal Antibody
CAT#: TA392848
Cdc40 (S209) polyclonal antibody
Size: 25 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500~1:1000 IHC: 1:50~1:200 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 181-230 of Human Cdc40. |
Specificity | Cdc40 (S209) polyclonal antibody detects endogenous levels of Cdc40 protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Predicted Protein Size | ~ 65 kDa |
Gene Name | cell division cycle 40 |
Database Link | |
Background | Cdc40, also known as pre-mRNA-processing factor 17 (PRPF17) or EH-binding protein 3 (EHB3), is a 579 amino acid nuclear protein. Cdc40 is essential for the catalytic step II of the pre-mRNA splicing process, in which Cdc40 associates with the spliceosome C complex. Cdc40 contains seven WD repeats, which are important in protein-protein interactions. Cdc40 has sequence similarity to the yeast protein Prp17, which is involved in pre-mRNA splicing and cell cycle progression. The sequence similarity between the mammalian Cdc40 and the yeast Prp17 may indicate an additional role in cell cycle progression for mammalian Cdc40. |
Synonyms | CDC40; Cell division cycle 40 homolog; EH-binding protein 3; EHB3; Ehb3; hPRP17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRPF17 |
Note | For research use only, not for use in diagnostic procedure. |
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