HOXD12 Rabbit Polyclonal Antibody
CAT#: TA392809S
HoxD12 (E230) polyclonal antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500~1:1000 IHC: 1:50~1:200 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 200-250 of Human HoxD12. |
Specificity | HoxD12 (E230) polyclonal antibody detects endogenous levels of HoxD12 protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Predicted Protein Size | ~ 30 kDa |
Gene Name | homeobox D12 |
Database Link | |
Background | The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis. |
Synonyms | Homeobox protein Hox-4H; Homeobox protein Hox-D12; HOX4H; HOXD12 |
Note | For research use only, not for use in diagnostic procedure. |
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