TFIIE beta (GTF2E2) Rabbit Polyclonal Antibody
CAT#: TA392747
TFIIE-β (K183) polyclonal antibody
Size: 25 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500~1:1000 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 153-213 of Human TFIIE-β. |
Specificity | TFIIE-β (K183) pAb detects endogenous levels of TFIIE-β protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Predicted Protein Size | ~ 33 kDa |
Gene Name | general transcription factor IIE subunit 2 |
Database Link | |
Background | The general transcription factor TFIIE consists of two subunits, α and β, and plays essential roles in transcription.Structure-function studies indicate that TFIIE has three-winged helix (WH) motifs, with one in TFIIEα and two in TFIIEβ. by binding to the clamp region of RNA polymerase II, TFIIEα-WH promotes the conformational change that transforms the promoter-bound inactive preinitiation complex to the active complex. |
Synonyms | General transcription factor IIE subunit 2; GTF2E2; TF2E2; TFIIE-beta; Transcription initiation factor IIE subunit beta |
Note | For research use only, not for use in diagnostic procedure. |
Reference Data |
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