SGK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 391-440 of Human SGK1.
Specificity	SGK1 (E416) polyclonal antibody detects endogenous levels of SGK1 protein
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 54 kDa
Gene Name	serum/glucocorticoid regulated kinase 1
Database Link	Entrez Gene 6446 Human UniProt ID O00141
Background	Serum- and glucocorticoid-regulated kinase (SGK), also known as SGK1, is a serine/threonine protein kinase and a member of the "AGC" subfamily, which includes protein kinases A, G, and C. SGK plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK contains a catalytic domain, which is most similar to Akt1. SGK is a downstream target of PI 3-kinase-stimulated growth factor signaling, with 3-phosphoinositide-dependent protein kinase 1 (PDK1) capable of phosphorylating the activation-loop of SGK at Threonine-256.
Synonyms	Serine/threonine-protein kinase Sgk1; Serine/threonine protein kinase SGK; Serine/threonine protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1; Serum/glucocorticoid regulated kinase; Serum/glucocorticoid regulated kinase 1; Serum and glucocorticoid regulated kinase; SGK; SGK 1; SGK1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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