Adenine Nucleotide Translocator 2 (SLC25A5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to Human SLC25A5.
Specificity	SLC25A5 polyclonal antibody detects endogenous levels of SLC25A5 protein.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 35 kDa
Gene Name	solute carrier family 25 member 5
Database Link	Entrez Gene 292 Human UniProt ID P05141
Background	Adenine nucleotide translocase 2 (ANT2/SLC25A5) is a member of the adenine nucleotide translocase family of mitochondrial inner membrane proteins that function differently in metabolic and apoptotic pathways. Research studies indicate that ANT2 expression in undifferentiated, proliferating cells correlates with the rate of glycolytic metabolism and may be an indicator of carcinogenesis. Suppression of ANT2/SLC25A5 expression by specific RNA interference in human breast cancer cells promotes apoptosis and inhibits tumor cell growth, which suggests a cytoprotective role of ANT2/SLC25A5.
Synonyms	Adenine nucleotide translocator 2; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein 2; ADP/ATP translocase 2; ANT 2; ANT2; DP/ATP translocase 2, N-terminally processed; Solute carrier family 25 member 5
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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