CASP3 Mouse Antibody [Clone ID: M377]

CAT#: TA389067

Anti-Caspase-3 (N-terminal region) Antibody



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CNY 3,413.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name M377
Applications ICC, WB
Recommend Dilution WB: 1:1000
ICC: 1:100
Reactivity Human
Host Mouse
Immunogen Clone (M377) was generated from a recombinant protein containing amino acid residues in the N-terminal region of human Caspase-3.
Specificity The antibody detects a 32 kDa* protein corresponding to the molecular weight of Caspase-3 on SDS-PAGE immunoblots of human Jurkat and K562 cells.
Formulation PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Concentration lot specific
Purification Protein A Purified
Conjugation Unconjugated
Storage Condition Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Predicted Protein Size 32
Background The caspases are a group of cysteine enzymes, which cleave proteins in response to intrinsic and extrinsic pathways that cause apoptotic cell death. The caspases can be grouped into two subgroups based on their roles in apoptosis. Initiator caspases (caspases 2, 8, 9, and 10) are activated through the apoptosis-signaling pathways and activate the effector caspases (caspases 3, 6, and 7) which carry out apoptosis. Caspase cascades are initiated through assembly of multiprotein complexes that trigger activation of the initiator caspases, which are then released and are able to activate the downstream effector caspases.
Note Protein G purified tissue culture supernatant.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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