CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: DF1513]

CAT#: TA388998

Anti-CD71 Antibody



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CNY 5,325.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name DF1513
Applications IHC, WB
Recommend Dilution WB: 1:1000
Host Mouse
Clonality Monoclonal
Immunogen Preparation of KG1 cells
Specificity Specific for endogenous levels of the ~98 kDa CD71 protein.
Formulation PBS
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Condition Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Predicted Protein Size 98
Gene Name transferrin receptor
Background CD71, also known as the transferrin receptor (TfR1), is a transmembrane glycoprotein whose primary function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin. CD71 is a widely used marker for cell activation or proliferation of lymphocytes as transferrin receptor expression is undetectable in resting T and B lymphocytes, but increases significantly upon lymphocyte antigen activation (Galbraith, R.M., et al 1981). Rapidly proliferating cells and energy-requiring cells, like cancer cells, osteoclasts (Roodman, G.D., 2009), and activated lymphocytes (Wieland, E., et al, 2016) express high levels of CD71 due to increased iron demand. TfR1 is seen as an efficient drug delivery system for cancer patients as it can mediate extracellular transferrin conjugated molecules for treatment (Luria-Perez, R., et al, 2016).
Synonyms CD71; p90; T9; TfR; TfR1; TR; Trfr
Note Protein G purified culture supernatant.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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