CD62L (SELL) Rabbit Monoclonal Antibody [Clone ID: DREG-56]

Specifications

Product Data
Clone Name	DREG-56
Applications	Bl, FC, IP, WB
Reactivity	Human, Chimpanzee, Bovine
Host	Rabbit
Clonality	Monoclonal
Immunogen	This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.
Specificity	This antibody is specific for human L-selectin, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules. This antibody has been used in WB, IP and binding assays to define a lymphocyte homing receptor for PLN HEVs (Kishimoto, 1990). In vitro, this antibody has been shown to specifically inhibit over 90% of binding of human lymphocytes to HEVs within frozen sections of peripheral, but not mucosal, lymphoid tissue (Kishimoto, 1990). This antibody has also been used in labelling studies to demonstate that the trophectoderm of implantation-competent human embryos expresses L-selectin (Genbacev, 2003).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	selectin L
Database Link	Entrez Gene 6402 Human UniProt ID P14151
Synonyms	CD62L; gp90-MEL; hLHRc; LAM-1; LAM1; LECAM1; Leu-8; LEU8; LNHR; LSEL; Lyam-1; LYAM1; PLNHR; TQ1
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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