CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: hu1124 (Efalizumab)]

Specifications

Product Data
Clone Name	hu1124 (Efalizumab)
Applications	Bl, FC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
Specificity	Binds to human LFA-1. Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	integrin subunit alpha L
Database Link	Entrez Gene 3683 Human UniProt ID P20701
Synonyms	CD11A; LFA-1; LFA-1A; LFA1A
Note	This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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